timi risk score for ischemia guided versus invasive

#TIMI RISK SCORE FOR ISCHEMIA GUIDED VERSUS INVASIVE FULL#

Consider adjunct medical therapy for ACS, e.g., sublingual nitroglycerin for chest pain relief.

Give aspirin if there are no contraindications.

Initiate supplemental O 2 for cyanosis, respiratory distress, or SpO 2 < 90%.

Start continuous telemetry and pulse oximetry.

Measure cardiac troponinas soon as possible upon clinical presentation.

Establish IV access and obtain blood samples for laboratory studies.

Obtain 12-lead ECG within 10 minutes of patient arrival.

Perform a focused clinical evaluation and ABCDE survey.

See “ Management of chest pain” for an approach to patients with undifferentiated chest pain. The following applies to patients with acute chest pain and suspected ACS.

Clinical triad in right ventricular infarction : hypotension, elevated jugular venous pressure, clear lung fields Ĭlassically, it has been taught that STEMI manifests with more severe symptoms than NSTEMI, but this is not always the case.

More common in inferior wall infarction.

Autonomic symptoms (e.g., nausea, diaphoresis).

Atypical presentations : more likely in elderly, diabetic individuals, and women.

New heart murmur on auscultation (e.g., new S 4 ).

Symptoms of CHF (e.g., orthopnea, pulmonary edema) or cardiogenic shock (e.g., hypotension, tachycardia, cold extremities).

The peak time of occurrence is usually in the morning.

Symptom relief after administration of nitrates is not a diagnostic criterion for cardiac ischemia.

Commonly radiates to left chest, arm, shoulder, neck, jaw, and/or epigastrium.

Typical: dull, squeezing pressure and/or tightness.

STEMI) is determined based on ECG findings. Unstable angina is differentiated from MI by the presence of positive troponins, while the type of MI ( NSTEMI vs. Subtypes of ACS cannot be differentiated based on clinical presentation alone.

See “ Acute management checklist for STEMI.”.

Adjunctive medical therapy similar to NSTE-ACS.

See “ Acute management checklist for NSTE-ACS.”.

Anticoagulants, antiplatelet therapy (e.g., aspirin, ADP receptor inhibitors).

Invasive management depends on risk stratification (e.g., TIMI score).

ST elevations (in two contiguous leads) or new left bundle branch block with strong clinical suspicion of myocardial ischemia.

Normal or nonspecific (e.g., ST depression, loss of R wave, T-wave inversion).

#TIMI RISK SCORE FOR ISCHEMIA GUIDED VERSUS INVASIVE FULL#

Affects the full thickness of the myocardium ( transmural infarction).Classically due to complete occlusion of a coronary artery.Affects the inner layer of the heart ( subendocardial infarction).

Classically due to partial occlusion of a coronary artery.Partial occlusion of coronary vessel → decreased blood supply → ischemic symptoms without infarction.Autonomic symptoms may be present: diaphoresis, syncope, palpitations, nausea, and/or vomiting.Severe, persistent, and/or worsening ( crescendo angina).Occurring at rest/with minimal exertion and is usually not relieved by rest or nitroglycerin.Symptoms are not reproducible/predictable.Acute myocardial ischemia that is severe enough to cause ST-segment elevations on ECG.Acute myocardial ischemia that is severe enough to cause detectable quantities of myocardial injury biomarkers but without ST-segment elevations on ECG.Acute myocardial ischemia that is not severe enough to cause detectable quantities of myocardial injury biomarkers or ST-segment elevations on ECG.ST-segment elevation myocardial infarction ( STEMI) Non-ST-segment elevation myocardial infarction ( NSTEMI) Overview of acute coronary syndrome ( ACS) See “ Myocardial infarction” for more details regarding, e.g., histopathology and long-term management. This article concerns the initial management of ACS patients. Adjunctive therapy (e.g., beta blockers, oxygen) helps reduce symptoms and can have a positive impact on mortality. All ACS patients receive dual antiplatelet therapy and initially anticoagulation. The timing and necessity of revascularization therapy in NSTE-ACS is determined based on multiple risk factors. STE-ACS patients require immediate revascularization therapy with percutaneous coronary intervention ( PCI) or fibrinolytic therapy. Depending on serum levels of cardiac troponin (cTn), NSTE-ACS can be categorized as NSTEMI or unstable angina (UA). Based on ECG findings, patients are categorized into those with ST-elevation ( STE-ACS) or non- ST-elevation ACS ( NSTE-ACS). Clinical findings (e.g., onset and characteristics of pain, patient history) in combination with ECG and troponin are the mainstays of diagnosis. Acute coronary syndrome ( ACS) is the clinical manifestation of myocardial infarct and commonly the default working diagnosis in patients with new-onset chest pain suspected to be of cardiac ischemic origin.

Timi risk score for ischemia guided versus invasive